Access is multi-user out of the box.

Assuming all of your users are in the same location, there should be no
reason to use replication.

Split your application into a front-end (containing the queries, forms,
reports, macros and modules) and a back-end (containing the tables). Only
the back-end should be on the server: each user should have a copy of the
front-end on his/her hard drive.

Tony Toews has good information about splitting databases at
http://www.granite.ab.ca/access/splitapp/index.htm (he also has a free Auto
FE Updater so that you can guarantee that each user has the current version
of the front-end at http://www.granite.ab.ca/access/autofe.htm )