If you're referring to the min, max and close buttons for the main Access
window, I don't believe it's possible. However, you could use a forms Unload
event to prevent Access from closing. Here is one example of how to do it.

Supposing you have your own close button called cmdClose on your form, add a
checkbox called chkCloseFlag somewhere on your form and set it's visible
property to no. In the forms On Open event set the check box to true;

Private Sub Form_Open()

  Me.chkCloseFlag = True

End Sub

Then in the Click event for the close button, set the checkbox to false
before closing the form;

Private Sub cmdClose_Click()

 Me.chkCloseFlag = False
 Docmd.Close

End Sub

Finally in the Unload event, verify the value of the checkbox;

Private Sub Frorm_Unload(Cancel As Integer)

 If me.chkCloseFlag = True Then
    Cancel = True
    MsgBox "Please use the Close button to exit the application"
 End If

End Sub

If the form can't close then Access can't close.

You can also set the border to none.